Methylation Panel

Overview

The Methylation Panel by Genova Diagnostics is an advanced test that provides a comprehensive assessment of the body's methylation pathway. By analyzing key biomarkers and genetic variations, this panel offers valuable insights into how your body is processing essential nutrients like folate and B12, which are critical for numerous bodily functions, including detoxification, energy production, and mood regulation.

What's Tested

• Homocysteine: An amino acid that, when elevated, can be a risk factor for cardiovascular disease.
• SAM/SAH Ratio: A key indicator of the body's methylation potential.
• Folate: An essential B vitamin that plays a crucial role in methylation.
• Vitamin B12: A vital nutrient that works with folate in the methylation cycle.

Who Should Order

• Individuals with a family history of cardiovascular disease or neurological disorders.
• Patients experiencing chronic fatigue, mood imbalances, or cognitive decline.
• Those with known MTHFR or other genetic SNPs affecting methylation.
• Individuals with symptoms of nutrient deficiencies, particularly B vitamins.

How It Works

The Methylation Panel requires a simple blood draw and a buccal (cheek) swab. The blood sample is used to measure the levels of key methylation biomarkers, while the buccal swab is used to identify common genetic single nucleotide polymorphisms (SNPs) that can affect methylation. Once the samples are received at the lab, the analysis is performed, and the results are typically available within 14-21 business days. Your healthcare provider will receive a detailed report that includes an easy-to-understand methylation pathway graphic, making it simple to identify any imbalances and create a personalized treatment plan.